Volume 7, Issue 5, September 2019, Page: 159-162
Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism
Li Hongyan, Department of Medical Technology, Cangzhou Medical College, Cangzhou, China; Cangzhou Thyroid Disease Engineering Research Center, Cangzhou, China
Zhang Chunhui, Department of Blood Transfusion of Hejian People's Hospital, Cangzhou, China
Wang Hongsheng, Thyroid Diagnosis and Treatment Center of Cangzhou Traditional Chinese Medicine-Western Hospital, Cangzhou, China
Xu Qian, Department of Medical Technology, Cangzhou Medical College, Cangzhou, China
Received: Sep. 26, 2019;       Published: Sep. 27, 2019
DOI: 10.11648/j.sjph.20190705.14      View  27      Downloads  6
Abstract
Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.
Keywords
Hypothyroidism, Subclinical Hypothyroidism, IL-2, IL-6, IL-8
To cite this article
Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian, Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism, Science Journal of Public Health. Vol. 7, No. 5, 2019, pp. 159-162. doi: 10.11648/j.sjph.20190705.14
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